Job v Gilgamesh: It's in the Reactions Where They Differ.

As with most biblical suffering, God is involved in some way. Actually, and I quote, "(God answers) 'You incited me to ruin him without cause, but he still holds fast to his integrity.' " (Bible) it seems that God is directly involved in the suffering that Job has to go through. Suffering from a divine source is definitely a common theme throughout the Bible and other ancient and prehistory stories. It will prove to be an important connection between the suffering of Gilgamesh and Job. As you all should know by now, the story goes as such: Job is one of the most pious in the land. The Devil approaches God and announces that he bets Job would turn away from God if his life took a turn for the worse. God agrees to torment Job per the Devil's request. It begins with the destruction of all that Job holds dear. In my interpretation, this is the worst part. Job has to stand by in perfect health as his family, livelihood, and possessions are torn away from him. All that he loves has been ripped from his helpless clutches. Job's servants, one arriving immediately after the other, report tragic news of his afflictions. This type of suffering is the worse of all. No matter what he does, he cannot save anything. He is utterly helpless against the wraith of the Devil. He has to persevere while he watches his family die around him. Gilgamesh has a similar experience of helplessness. The gods decide that they must kill his best friend and brother, Enkidu. There is nothing that Gilgamesh can do to stop the gods acting on their intentions. Gilgamesh is heart-broken and decides to rebel against human mortality. This is where Gilgamesh and Job differ. Their sufferings are quite similar, the common theme being helplessness and being unable to save those whom you love, but their reactions are opposite. Job resigns himself to God's will. He accepts this depressing fate whereas Gilgamesh rebels against it.
 Through all of this darkness, Job's faith ends up being the only source of hope he has left. But, the Devil announces that it is not enough. He decides he must harm Job physically. He swiftly inflicts him with sores and other ailments. The reason why Job is able to hang onto life and virtue is through his devout faith in God. Gilgamesh does not have the same type of faith in the gods, therefore his reaction is different because his theology is so different from Judaism's, Job's religion. As it seems, the theology of Gilgamesh warrants a connection to gods that validates questioning and supports a person's role in controlling their own fate. Judaism warrants complete faith in God and a hope that God is loving and will not do us wrong. Gilgamesh quests to set things right while Job waits out the suffering on his belief that God will come through in the end.
There suffering is much the same. Their inner beliefs yield very different reactions to the troubles that are forced upon them.